Technetium-99m-GSA clearance in mice under long-term dietary restriction
作者： Katsuyasu Kouda , Hirao Kohno , Harunobu Nakamura , Sang K. Ha-Kawa , Yoshiaki Sonoda
DOI: 10.1007/S12149-008-0217-1
关键词:
摘要: Objective Dietary restriction (DR) without malnutrition is widely acknowledged to prolong lifespan in laboratory animals. Evidence suggests that DR retards age-related decline protein turnover of most organs. However, there has been no report about hepatic serum glycoprotein catabolism under DR. In the current study, we evaluate uptake asialoglycoprotein ICR mice with by measuring plasma clearance technetium-99m galactosyl human albumin (Tc-GSA).
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