C-Reactive Protein as a Cardiovascular Risk Factor More Than an Epiphenomenon?

摘要: Background—Circulating levels of C-reactive protein (CRP) may constitute an independent risk factor for cardiovascular disease. How CRP as a is involved in disease still unclear. Methods and Results—By reviewing available studies, we discuss explanations the associations between within upper quartile/quintile normal range increased events, both apparently healthy persons with preexisting angina pectoris. High responses after acute myocardial infarction indicate unfavorable outcome, even correction other factors. This link has been considered to reflect response body inflammatory reactions atherosclerotic (coronary) vessels adjacent myocardium. However, because localizes infarcted myocardium (with colocalization activated complement), hypothesize that dire...