Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.
作者： Marc P. Hübner , Coralie Martin , Sabine Specht , Marianne Koschel , Bettina Dubben
DOI: 10.1371/JOURNAL.PNTD.0008427
关键词:
摘要: … we tested oxfendazole, an anthelmintic shown to be well tolerated in phase 1 clinical trials. In vitro, oxfendazole … In addition, 10 days of oral treatments with oxfendazole inhibited filarial …
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