Glaucoma in Asia: regional prevalence variations and future projections.

摘要: Purpose To evaluate glaucoma prevalence and disease burden across Asian subregions from 2013 to 2040. Methods We conducted a systematic review meta-analysis of 23 population-based studies 1318 primary open angle (POAG) cases in 66 800 individuals 691 closure (PACG) 72 767 Asia. Regions Asia were defined based on United Nations’ (UN) classification macro-geographic regions. PubMed, Medline Web Science databases searched for using standardised criteria published 31 December 2013. Pooled aged 40–80 years was calculated hierarchical Bayesian approaches. Prevalence differences by geographic subregion, subtype habitation examined with random effects meta-regression models. Estimates 2040 the UN World Population Prospects. Results In 2013, pooled overall 3.54% (95% credible interval (CrI) 1.83 6.28). POAG (2.34%, 95% CrI 0.96 4.55) predominated over PACG (0.73%, 0.18 1.96). With age gender adjustment, higher East than South (OR 5.55, 1.52 14.73), urban rural populations 2.11, 1.57 2.38). From 2040, Central will record steepest increase number 17.06 million 32.90 compared other subregions. South-Central is also projected overtake highest burden, while remains Conclusions Across subregions, there greater Sustainable public health strategies combat are needed.