Drug discovery method
作者： Robert B. Perni , John A. Thomson , Cynthia Gates
DOI:
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摘要: The application discloses a method for selecting Hepatitis C (HCV) inhibitors that form long-lived, tight complexes (EI complex) with their targets (eg NS3/4a protease). It also the compound VX-950 which has such properties and its medical use treating HCV infection eliminating contamination. of cellular viral replication assays are equally claimed.
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