Compact but Complex – The Marsupial Y Chromosome

摘要: The mammalian Y chromosome is a gene poor element with enormous responsibility. Just how the acquired function of sex determination, then surrendered most its other functions, remains one intriguing questions in genomics. basic marsupial represents degraded relic original Y, which did not receive large autosomal addition that augmented X and eutherian mammals. Like mammals, contains species-specific repetitive sequences. It also bears an interesting mixture genes; ancient male-specific genes, such as SRY RBMY, evolved from X-borne genes before eutherian-marsupial divergence, are conserved across therian novel ATRY, mammals have been lost but maintain copy on X. unique properties provided insights into evolution enabling us to gain better understanding selection processes shaped it.