House dust mite allergy and atopic eczema: a case report.

摘要: SUMMARY Scquential measurements were made of total and specific serum IgE concentrations in an adult patient with severe atopic eczema. Initially, the conccntration concentration antibody to house dust mite very high. These conccntrations decreased over next 3 years, following amelioration her However, they rose again when eczema worsencd as a rcsult marital problems fell oncc after scparation from husband. The other common allergens, however, remained stable during this pcriod. results suggest that large amounts antigen may be scratched into skin clinical exacerbations eczema, turn aggravating state because hypersensitivity mite. The pathogcncsis remains enigma. Although histological changes do not immediately mediated mechanism, mast cells are increased number1 major basic protein derived cosinophils is also demonstrable,2 It well recognized patients persistent have higher than thosc mild eczema3,4 proportion these antibodies directed against (HDM) antigens.5 has been suggested results, at least part, HDM antigens being skin;6 would create vicious circle those mite. Sequential performed related severity disease.