THE NORMAL AND PATHOLOGICAL PHYSIOLOGY OF THE NUCLEUS PULPOSUS OF THE INTERVERTEBRAL DISC

摘要: 1. The assumption of von Luschka and later embryologists that the intervertebral nucleus pulposus is a vestigial remnant notochord has been disproved. It highly specialized structure. 2. not formed from degeneration annulus fibrosus fibers as postulated by Virchow Dursy. 3. This anatomical entity proliferation mucoid cells, followed fibrocartilaginous invasion derived original mesenchymal which form fibrocartilage envelope. 4. cartilage plate epiphyseal ring are genetically one structure comparable to epiphyses long bones. 5. nuclei pulposi essential for normal physiological functions spine. 6. Loss material result trauma or disease probably frequent etiological factors associated with pain in back disability. 7. Clinical experimental evidence presented indicate degenerative, hypertrophic arthritis spine may loss shock absorber hydrodynamic ball bearing spine, pulposus. 8. If disc dog injured scalpel drill, nuclear prolapses into spongiosa nodule forms. 9. allowed escape, rest becomes thinned out margins adjacent vertebrae become sclerosed subsequent marginal lipping.