Percutaneous Coronary Intervention After Subcutaneous Enoxaparin Pretreatment in Patients With Unstable Angina Pectoris

摘要: Background—Subcutaneous low-molecular-weight (LMW) heparins can effectively replace unfractionated heparin in patients with unstable angina or non–Q-wave myocardial infarction. However, the optimal anticoagulation strategy for these when they require cardiac catheterization is still unclear. Therefore, we evaluated a new and simple of patients. Methods Results—A total 451 consecutive angina/non–Q-wave infarction were treated at least 48 hours subcutaneous injections enoxaparin (1 mg [100 IU]/kg every 12 hours, cycled 6 AM PM). Of this unselected population, 293 (65%) underwent coronary angiography within 8 morning LMW injection, followed by immediate percutaneous intervention (PCI) 132 (28%). PCI was performed without any additional bolus unfractionated/LMW coagulation monitoring. Anti-Xa activity time catheterization...