Vitamin D inhibition of prostate adenocarcinoma growth and metastasis in the Dunning rat prostate model system

作者: Robert H. Getzenberg , Benjamin W. Light , Paul E. Lapco , Badrinath R. Konety , Ajay K. Nangia

DOI: 10.1016/S0090-4295(97)00408-1

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摘要: Objectives Risk factors for prostate cancer (PCa)-related mortality include old age, black race, and residence in northern latitudes. The objectives of this study are to examine the vitro vivo effects 1, 25-dihydroxycholecalciferol (1,25-D3) less-hypercalcemic analogues on Dunning rat adenocarcinoma model.

参考文章(29)
Hedlund Te, Ferrara Ja, Upadhya P, Pfister S, Lucia Ms, Stapleton Ge, Miller Gj, The Human Prostatic Carcinoma Cell Line LNCaP Expresses Biologically Active, Specific Receptors for 1α,25-Dihydroxyvitamin D3 Cancer Research. ,vol. 52, pp. 515- 520 ,(1992)
George P. Studzinski, Amarjit K. Bhandal, Zamir S. Brelvi, Cell Cycle Sensitivity of HL-60 Cells to the Differentiation-inducing Effects of 1-α,25-Dihydroxyvitamin D3 Cancer Research. ,vol. 45, pp. 3898- 3905 ,(1985)
H P Koeffler, M Uskokovic, L Binderup, T Umiel, M Linker-Israeli, D Heber, E Elstner, I P Shintaku, J Said, S de Vos, 20-epi-Vitamin D3 Analogues: A Novel Class of Potent Inhibitors of Proliferation and Inducers of Differentiation of Human Breast Cancer Cell Lines Cancer Research. ,vol. 55, pp. 2822- 2830 ,(1995)
Norbert W. Tietz, Fundamentals of Clinical Chemistry ,(1970)
George P. Studzinski, Qing Mei Wang, Jennifer B. Jones, Cyclin-dependent Kinase Inhibitor p27 as a Mediator of the G1-S Phase Block Induced by 1,25-Dihydroxyvitamin D3 in HL60 Cells Cancer Research. ,vol. 56, pp. 264- 267 ,(1996)
Donna M. Peehl, Thomas A. Stamey, David Feldman, Roman J. Skowronski, Gordon K. Leung, Stephen T. Wong, Antiproliferative Effects of 1,25-Dihydroxyvitamin D3 on Primary Cultures of Human Prostatic Cells Cancer Research. ,vol. 54, pp. 805- 810 ,(1994)
Badrinath R Konety, Gary G Schwartz, James S Acierno Jr, Michael J Becich, Robert H Getzenberg, None, The role of vitamin D in normal prostate growth and differentiation. Cell Growth & Differentiation. ,vol. 7, pp. 1563- 1570 ,(1996)
Mario A. Anzano, Christopher W. Peer, Mark W. Shrader, Darlene M. Green, Anita B. Roberts, Michael B. Sporn, Daniel L. Logsdon, Charles C. Brown, Craig L. Driver, Michael V. Slayter, M. Scott Lucia, Miriam R. Anver, Chemopreventive activity of tamoxifen, N-(4-hydroxyphenyl)retinamide, and the vitamin D analogue Ro24-5531 for androgen-promoted carcinomas of the rat seminal vesicle and prostate Cancer Research. ,vol. 55, pp. 5621- 5627 ,(1995)
Mariann C. McElwain, Benjamin W. Light, Wei-Dong Yu, Candace S. Johnson, Derrick M. Russell, Donald L. Trump, Potentiation of Cisplatin Antitumor Activity Using a Vitamin D Analogue in a Murine Squamous Cell Carcinoma Model System Cancer Research. ,vol. 57, pp. 3759- 3764 ,(1997)