Low-frequency electroacupuncture and physical exercise decrease high muscle sympathetic nerve activity in polycystic ovary syndrome

摘要: We have recently shown that polycystic ovary syndrome (PCOS) is associated with high muscle sympathetic nerve activity (MSNA). Animal studies support the concept low-frequency electroacupuncture (EA) and physical exercise, via stimulation of ergoreceptors somatic afferents in muscles, may modulate nervous system. The aim present study was to investigate effect these interventions on women PCOS. In a randomized controlled trial, 20 PCOS were randomly allocated one three groups: EA (n = 9), exercise 5), or untreated control 6) during 16 wk. Direct recordings multiunit efferent postganglionic MSNA fascicle peroneal before following wk treatment. Biometric, hemodynamic, endocrine, metabolic parameters measured. Low-frequency (P 0.036) 0.030) decreased burst frequency compared group. group reduced sagittal diameter 0.001), while body weight 0.004) mass index Sagittal related (Rs 0.58, P < 0.005) No correlation found for There no differences between groups variables. For first time we demonstrate lowers Thus, treatment reduce be importance