Vitamin D and diabetes mellitus: Causal or casual association?

摘要: The incidence of both type 2 and 1 diabetes mellitus has been increasing worldwide. Vitamin D deficiency, or the awareness its prevalence, also increasing. may have a role in pathogenic mechanisms predisposing to by modulating insulin resistance and/or pancreatic β-cell function. status elements involved activation transport be development through immunomodulatory . Based on these observations potential association between vitamin hypothesized. In this review we discuss up date evidence linking with diabetes. Moreover, supplementation prevention types is analysed together improving glycemic control diabetic patients. We address deficiency macro- microvascular complications Finally, provide recommendation for therapy view current highlight areas future research area.