Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas

作者: Mona Sæbø , Camilla Furu Skjelbred , Bjørn Andersen Nexø , Håkan Wallin , Inger-Lise Hansteen

DOI: 10.1186/1471-2407-6-208

关键词:

摘要: Background The majority of colorectal cancer (CRC) cases develop through the adenoma-carcinoma pathway. If an increase in DNA repair expression is detected both early adenomas and carcinomas it may indicate that low capacity normal mucosa a risk factor for adenoma formation.

参考文章(38)
Yu Jj, Reed E, Li Q, Yunmbam Mk, Slavsky D, Cross Cl, Bostick-Bruton F, Mu C, Association between the level of ERCC-1 expression and the repair of cisplatin-induced DNA damage in human ovarian cancer cells. Anticancer Research. ,vol. 20, pp. 645- 652 ,(2000)
Margaret R. Spitz, Qingyi Wei, Lie Cheng, Waun Ki Hong, Reduced DNA Repair Capacity in Lung Cancer Patients Cancer Research. ,vol. 56, pp. 4103- 4107 ,(1996)
R Metzger, C G Leichman, K D Danenberg, P V Danenberg, H J Lenz, K Hayashi, S Groshen, D Salonga, H Cohen, L Laine, P Crookes, H Silberman, J Baranda, B Konda, L Leichman, ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. Journal of Clinical Oncology. ,vol. 16, pp. 309- 316 ,(1998) , 10.1200/JCO.1998.16.1.309
Simone Benhamou, Alain Sarasin, Variability in nucleotide excision repair and cancer risk: a review. Mutation Research-reviews in Mutation Research. ,vol. 462, pp. 149- 158 ,(2000) , 10.1016/S1383-5742(00)00032-6
Eric R. Fearon, Bert Vogelstein, A genetic model for colorectal tumorigenesis Cell. ,vol. 61, pp. 759- 767 ,(1990) , 10.1016/0092-8674(90)90186-I
Qiuling Shi, Li-E Wang, Melissa L Bondy, Abenaa Brewster, S Eva Singletary, Qingyi Wei, Reduced DNA repair of benzo[a]pyrene diol epoxide-induced adducts and common XPD polymorphisms in breast cancer patients Carcinogenesis. ,vol. 25, pp. 1695- 1700 ,(2004) , 10.1093/CARCIN/BGH167
Jian-Ping Yang, Mayumi Hori, Takaomi Sanda, Takashi Okamoto, Identification of a Novel Inhibitor of Nuclear Factor-κB, RelA-associated Inhibitor Journal of Biological Chemistry. ,vol. 274, pp. 15662- 15670 ,(1999) , 10.1074/JBC.274.22.15662
Shohei Kondo, Shinya Toyokuni, Yoko Iwasa, Tomoyuki Tanaka, Hisashi Onodera, Hiroshi Hiai, Masayuki Imamura, Persistent oxidative stress in human colorectal carcinoma, but not in adenoma Free Radical Biology and Medicine. ,vol. 27, pp. 401- 410 ,(1999) , 10.1016/S0891-5849(99)00087-8
Ulla Vogel, Peter Møller, Lars Dragsted, Steffen Loft, Anette Pedersen, Brittmarie Sandström, None, Inter-individual variation, seasonal variation and close correlation of OGG1 and ERCC1 mRNA levels in full blood from healthy volunteers. Carcinogenesis. ,vol. 23, pp. 1505- 1509 ,(2002) , 10.1093/CARCIN/23.9.1505
Rikke Hansen, Mona Sæbø, Camilla Furu Skjelbred, Bjørn Andersen Nexø, Per Christian Hagen, Günther Bock, Inger Marie Bowitz Lothe, Egil Johnson, Steinar Aase, Inger-Lise Hansteen, Ulla Vogel, Elin H Kure, None, GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer Cancer Letters. ,vol. 229, pp. 85- 91 ,(2005) , 10.1016/J.CANLET.2005.04.019