Lipoprotein abnormalities in patients with atherosclerotic renovascular disease.
作者： Elzbieta Nowakowska Fortuna , Hans Herlitz , Aso Saeed , Per-Ola Attman , Gert Jensen
DOI: 10.1159/000325648
关键词:
摘要: Background: Patients with atherosclerotic renovascular disease (ARVD) have a high risk of cardiovascular death. The primary aim was to characterize abnormalities in apolipoprotein (Apo)-defined lipoprotein (Lp) subclasses patients ARVD. Methods: Baseline measurements were performed on 42 ARVD 4 weeks after renal angioplasty (PTRA). All statin treatment. Twenty age-matched healthy subjects without medications served as controls. Subsequently, randomized treatment either candesartan (n = 21), or antihypertensive inhibitors the renin-angiotensin-aldosterone system 21) and followed for 11 months. Results: At baseline, ApoC-III (12.7 ± 4.6 vs. 8.8 2.6 (SD) mg/dl, p Conclusions: treated statins an atherogenic profile characterized by elevated levels ApoC-III-containing, triglyceride-rich lipoproteins that could accelerate disease.
sci-hub.se 参考文章(37)
Lipoprotein abnormalities without hyperlipidaemia in moderate renal insufficiency Nephrology Dialysis Transplantation. ,vol. 9, pp. 1580- 1585 ,(1994) , 10.1093/NDT/9.11.1580
Doris T. Chan, Ashley B. Irish, Gursharan K. Dogra, Gerald F. Watts, Dyslipidaemia and cardiorenal disease :mechanisms, therapeutic opportunities and clinical trials Atherosclerosis. ,vol. 196, pp. 823- 834 ,(2008) , 10.1016/J.ATHEROSCLEROSIS.2007.01.023
Alaa Alhadad, Gregor Guron, Ella Fortuna-Nowakowska, Aso Saeed, Ingrid Mattiasson, Gert Jensen, Bengt Lindblad, Anders Gotts??ter, Hans Herlitz, Renal angioplasty causes a rapid transient increase in inflammatory biomarkers, but reduced levels of interleukin-6 and endothelin-1 1 month after intervention Journal of Hypertension. ,vol. 25, pp. 1907- 1914 ,(2007) , 10.1097/HJH.0B013E328244E2CA
Per-Ola Attman, Petar Alaupovic, Lipid and apolipoprotein profiles of uremic dyslipoproteinemia--relation to renal function and dialysis. Nephron. ,vol. 57, pp. 401- 410 ,(1991) , 10.1159/000186303
P. Alaupovic, P.O. Attman, C. Knight-Gibson, H. Mulec, L. Weiss, O. Samuelsson, Effect of fluvastatin on apolipoprotein-defined lipoprotein subclasses in patients with chronic renal insufficiency. Kidney International. ,vol. 69, pp. 1865- 1871 ,(2006) , 10.1038/SJ.KI.5000327
J.E. Scoble, D. de Takats, M.E. Ostermann, J.O. Connolly, N.R. Scott, J.A. Beeso, K.H. Poyser, T.J. Peters, R.A. Sherwood, Lipid profiles in patients with atherosclerotic renal artery stenosis. Nephron. ,vol. 83, pp. 117- 121 ,(1999) , 10.1159/000045487
Herbert Schuster, Björn Fagerberg, Siôn Edwards, Tamas Halmos, Jerzy Lopatynski, Steen Stender, Grethe Stoa Birketvedt, Serena Tonstad, Ingrid Gause-Nilsson, Sigrún Halldórsdóttir, K. Peter Öhman, Tesaglitazar, a dual peroxisome proliferator-activated receptor α/γ agonist, improves apolipoprotein levels in non-diabetic subjects with insulin resistance Atherosclerosis. ,vol. 197, pp. 355- 362 ,(2008) , 10.1016/J.ATHEROSCLEROSIS.2007.05.029
Mats Johanssona, Hans Herlitzb, Gert Jensenb, Bengt Rundqvist, Peter Friberga, Increased cardiovascular mortality in hypertensive patients with renal artery stenosis. Relation to sympathetic activation, renal function and treatment regimens. Journal of Hypertension. ,vol. 17, pp. 1743- 1750 ,(1999) , 10.1097/00004872-199917120-00012
Petar Alaupovic, Wendy J. Mack, Carolyn Knight-Gibson, Howard N. Hodis, The Role of Triglyceride-Rich Lipoprotein Families in the Progression of Atherosclerotic Lesions as Determined by Sequential Coronary Angiography From a Controlled Clinical Trial Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 17, pp. 715- 722 ,(1997) , 10.1161/01.ATV.17.4.715
Per-Ola Attman, Ola Samuelsson, Petar Alaupovic, Lipoprotein Metabolism and Renal Failure American Journal of Kidney Diseases. ,vol. 21, pp. 573- 592 ,(1993) , 10.1016/S0272-6386(12)80030-8