Brain natriuretic peptides in atherosclerotic renal artery stenosis and effects of renal angioplasty.
作者： Elzbieta Nowakowska-Fortuna , Aso Saeed , Gregor Guron , Michael Fu , Ola Hammarsten
DOI: 10.1159/000355746
关键词:
摘要: Background: We hypothesized that plasma levels of brain natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP) would be elevated, adiponectin concentrations reduced, in patients with atherosclerotic renal artery stenosis (ARAS) BNPs might used to identify who benefit from percutaneous transluminal angioplasty (PTRA). Methods: Data were collected before angiography 91 hypertension suspected ARAS (significant ARAS; n=47, non-RAS; n=44) 20 healthy controls (C). In analyses repeated four weeks after PTRA. Results: Ambulatory systolic blood pressure (ASBP) was significantly elevated the group vs. both C non-RAS groups. Baseline BNP NT-proBNP but not group. One month PTRA, ASBP reduced baseline (149±16 139±15 mm pConclusions: Patients showed concentrations, adiponectin, compared hypertensive individuals without RAS. Our data do no support use identification will have a beneficial response
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