Neonatal, placental, and umbilical cord blood parameters in pregnant women residing in areas with intensive pesticide application.

作者: María Martha Quintana , Berta Vera , Gladis Magnarelli , Natalia Guiñazú , María Gabriela Rovedatti

DOI: 10.1007/S11356-017-9642-9

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摘要: In rural populations, the proximity to areas with intensive pesticide application represents a risk factor of xenobiotic exposure. Here, we investigated whether newborns born mothers residing in an area show alterations placental and neonatal morphometric standards, umbilical cord blood (UCB) biochemical parameters, and/or biomarkers related oxidative stress damage. Samples were collected from 151 healthy pregnant women (rural group; RG) during spraying (SS) nonspraying (NSS) seasons, as well urban population (control CG), grouped according delivery type (vaginal or cesarean). vaginal group, weight index higher RG groups than CG (p = 0.01), whereas cesarean newborn was lower RG-SS group CG. UCB erythrocyte osmotic fragility DNA damage (DI) higher, superoxide dismutase (SOD) activity RG-NSS group. Acetylcholinesterase SOD activities found be inversely correlated DI.

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