Passive propagation of LTD to stratum oriens-alveus inhibitory neurons modulates the temporoammonic input to the hippocampal CA1 region

作者: Gianmaria Maccaferri , Chris J. McBain

DOI: 10.1016/0896-6273(95)90071-3

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摘要: Excitatory synaptic activity in horizontal stratum oriens-alveus interneurons (OAIs) is driven by the recurrent collaterals of CA1 pyramidal cells and strongly influenced protocols that elicit plasticity these principal neurons. Induction LTD Schaffer collateral-CA1 neuron synapse causes a passive down-regulation radiatum-evoked excitatory responses onto OAIs. In addition, we show strength temporoammonic input to distal dendrites regulated OAI activity. The propagation OAIs consequently disinhibits direct entorhinal cortex-CA1 input, resulting an enhanced excitation neurons mechanism not requiring activation trisynaptic pathway.

参考文章(40)
Philip A. Schwartzkroin, Helen E. Scharfman, Robert S. Sloviter, Chapter 20 Similarities in circuitry between Ammon's horn and dentate gyrus: local interactions and parallel processing Progress in Brain Research. ,vol. 83, pp. 269- 286 ,(1990) , 10.1016/S0079-6123(08)61256-X
Christer Köhler, Victoria Chan-Palay, The Hippocampus : new vistas A.R. Liss. ,(1989)
Stephen J. Korn, Alain Marty, John A. Connor, Richard Horn, Perforated Patch Recording Methods in Neurosciences. ,vol. 4, pp. 364- 373 ,(1991) , 10.1016/B978-0-12-185257-3.50027-6
A. I. Gulyás, R. Miles, A. Sik, K. Tóth, N. Tamamaki, T. F. Freund, Hippocampal pyramidal cells excite inhibitory neurons through a single release site Nature. ,vol. 366, pp. 683- 687 ,(1993) , 10.1038/366683A0
CCG Naus, JH Morrison, FE Bloom, None, Development of somatostatin-containing neurons and fibers in the rat hippocampus Developmental Brain Research. ,vol. 40, pp. 113- 121 ,(1988) , 10.1016/0165-3806(88)90013-2