作者: Gianmaria Maccaferri , Chris J. McBain
DOI: 10.1016/0896-6273(95)90071-3
关键词:
摘要: Excitatory synaptic activity in horizontal stratum oriens-alveus interneurons (OAIs) is driven by the recurrent collaterals of CA1 pyramidal cells and strongly influenced protocols that elicit plasticity these principal neurons. Induction LTD Schaffer collateral-CA1 neuron synapse causes a passive down-regulation radiatum-evoked excitatory responses onto OAIs. In addition, we show strength temporoammonic input to distal dendrites regulated OAI activity. The propagation OAIs consequently disinhibits direct entorhinal cortex-CA1 input, resulting an enhanced excitation neurons mechanism not requiring activation trisynaptic pathway.