Effect of intravenous injection of acetate on the pancreas of sheep.

作者: H. MINEO , A. KITADE , S. KAWAKAMI , S. KATO , J. USHIJIMA

DOI: 10.1016/S0034-5288(18)31019-1

关键词:

摘要: The effect of an intravenous injection acetate on plasma insulin and glucagon concentration was examined in conscious sheep. Sodium (312 to 5000 mumol kg-1 bodyweight) increased concentrations a dose-dependent manner. Plasma not affected by doses up 1250 kg-1. Doses 2500 produced significant increases (P less than 0.05), but dose related results this study indicate that the receptive mechanism A cell sheep pancreas might be different from B cell.

参考文章(15)
John W. McAtee, Allen Trenkle, Metabolic regulation of plasma insulin levels in cattle. Journal of Animal Science. ,vol. 33, pp. 438- 442 ,(1971) , 10.2527/JAS1971.332438X
EN Bergman, JE Wolff, Metabolism of volatile fatty acids by liver and portal-drained viscera in sheep American Journal of Physiology. ,vol. 221, pp. 586- 592 ,(1971) , 10.1152/AJPLEGACY.1971.221.2.586
M. HORINO, L. J. MACHLIN, F. HERTELENDY, D. M. KIPNIS, Effect of short-chain fatty acids on plasma insulin in ruminant and nonruminant species. Endocrinology. ,vol. 83, pp. 118- 128 ,(1968) , 10.1210/ENDO-83-1-118
S R Bloom, A V Edwards, Pancreatic neuroendocrine responses to butyrate in conscious sheep. The Journal of Physiology. ,vol. 364, pp. 281- 288 ,(1985) , 10.1113/JPHYSIOL.1985.SP015744
Y Sasaki, H Takahashi, Insulin secretion in sheep exposed to cold. The Journal of Physiology. ,vol. 306, pp. 323- 335 ,(1980) , 10.1113/JPHYSIOL.1980.SP013399
D.G. Patel, Sant P. Singh, Effect of ethanol and its metabolites on glucose mediated insulin release from isolated islets of rats. Metabolism-clinical and Experimental. ,vol. 28, pp. 85- 89 ,(1979) , 10.1016/0026-0495(79)90173-2
J. H. Shah, N. Wongsurawat, P. P. Aran, Effect of Ethanol on Stimulus-induced Insulin Secretion and Glucose Tolerance: A Study of Mechanisms Diabetes. ,vol. 26, pp. 271- 277 ,(1977) , 10.2337/DIAB.26.4.271
Y. SASAKI, H. TAKAHASHI, H. ASO, A. OHNEDA, T. E. C. WEEKES, Effects of cold exposure on insulin and glucagon secretion in sheep. Endocrinology. ,vol. 111, pp. 2070- 2076 ,(1982) , 10.1210/ENDO-111-6-2070