Clues to Tumors: New Concepts of Symptoms, Signs, Syndromes, Paraneoplastic Syndromes, and Predisposition to Ovarian Cancer

摘要: ABSTRACT There are no early symptoms and/or unique of ovarian tumors except possibly those which hormonally active or sudden, new symptoms. is a possible paraneoplastic syndrome for diagnosis the common “dyspepsia.” Physical examination epithelial cancer unreliable, especially early. Transvaginal ultrasound and serum tumor markers (CA125) helpful but not completely reliable. It often unappreciated that recognition may alert physician to increased chance tumor. For with high risk, prophylactic surgery an option after childbearing. An even more important potentially overlooked diagnostic opportunity appear in (or infrequently before) formation. Although considered be rare, it maybe than expected subclinical cases might detected by tests. hereditary genetic associated autosomal dominant, highly penetrant gene mutations BRCA1 BRCA2 as well certain syndromes, there larger number combinations less recessive mutations, difficult identify pedigree.