Lobophytones H-N, Biscembranoids from the Chinese Soft Coral Lobophytum pauciflorum
作者： Pengcheng Yan , Zhiwei Deng , Leen van Ofwegen , Peter Proksch , Wenhan Lin
DOI: 10.1248/CPB.58.1591
关键词:
摘要: Chemical examination of a Chinese soft coral Lobophytum pauciflorum resulted in the isolation seven new biscembranoids, named lobophytones H—N (1—7). Their structures were determined by interpretation 1D- and 2D-NMR (correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), multiple bond connectivity (HMBC), nuclear Overhauser effect (NOESY)) spectroscopic data association with MS IR data. All compounds tested for inhibition lipopolysaccharide (LPS)-induced nitric oxide (NO) production, cytotoxicity mouse peritoneal macrophage, antibacterial activities.
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