Therapie des Magenkarzinoms über die aktuelle Leitlinie hinaus

摘要: The majority of recommendations in the current S3 guideline on diagnosis and treatment gastric carcinoma are based good clinical practice lack supporting randomized studies. With development endoscopic resection multimodal concepts, pretherapeutic tumor staging has gained importance. However, accuracy present imaging modalities is still limited with a tendency towards overstaging locally advanced tumors. Extended lymph node dissection cannot be recommended cases involvement. In cardiac cancer retroperitoneal lymphatic spread to left renal vein an early event should thus not classified as stage IV disease. intra-abdominal gastrectomy pouch reconstruction considered overall prognosis. Subgroup analyses indicate differential therapeutic effect established perioperative chemotherapy depending location primary tumor. There also evidence for additional beneficial radiotherapy combination chemotherapy.