Fatty acid ethyl ester, a non-oxidative ethanol metabolite, reverses the inhibitory effect of ibuprofen on platelet aggregation.

作者: R. O. SALEM , M. LAPOSATA

DOI: 10.1111/J.1538-7836.2005.01724.X

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参考文章(11)
Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. Seminars in Vascular Medicine. ,vol. 3, pp. 107- 112 ,(2003) , 10.1055/S-2003-40668
Daniel Deykin, Paul Janson, Louise McMahon, Ethanol potentiation of aspirin-induced prolongation of the bleeding time. The New England Journal of Medicine. ,vol. 306, pp. 852- 854 ,(1982) , 10.1056/NEJM198204083061406
J. R. Vane, Mode of action of aspirin-like drugs. Advances in internal medicine. ,vol. 24, pp. 1- 22 ,(1978) , 10.1007/BF01968671
W.V. Kageler, J.L. Moake, C.A. Garcia, Spontaneous Hyphema Associated by Ingestion of Aspirin and Ethanol American Journal of Ophthalmology. ,vol. 82, pp. 631- 634 ,(1976) , 10.1016/0002-9394(76)90553-5
D. Henry, L. L-Y Lim, L. A G. Rodriguez, S. P. Gutthann, J. L Carson, M. Griffin, R. Savage, R. Logan, Y. Moride, C. Hawkey, S. Hill, J. T Fries, J. T Fries, Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis. BMJ. ,vol. 312, pp. 1563- 1566 ,(1996) , 10.1136/BMJ.312.7046.1563
Risto Roine, Aspirin Increases Blood Alcohol Concentrations in Humans After Ingestion of Ethanol JAMA: The Journal of the American Medical Association. ,vol. 264, pp. 2406- 2408 ,(1990) , 10.1001/JAMA.1990.03450180070031
David W Kaufman, Judith Parsells Kelly, Bengt-Erik Wiholm, András Laszlo, Jane E Sheehan, Raymond S Koff, Samuel Shapiro, The risk of acute major upper gastrointestinal bleeding among users of aspirin and ibuprofen at various levels of alcohol consumption The American Journal of Gastroenterology. ,vol. 94, pp. 3189- 3196 ,(1999) , 10.1111/J.1572-0241.1999.01517.X
Joanne E. Cluette-Brown, Michael Laposata, Britt L. Soderberg, Raneem O. Salem, Catherine A. Best, Fatty acid ethyl esters. Ethanol metabolites that reflect ethanol intake. American Journal of Clinical Pathology. ,vol. 119, pp. 94- 99 ,(2003) , 10.1309/6F39-EAR2-L4GY-X5G6
J. L. Humes, C. A. Winter, S. J. Sadowski, F. A. Kuehl, Multiple sites on prostaglandin cyclooxygenase are determinants in the action of nonsteroidal antiinflammatory agents Proceedings of the National Academy of Sciences of the United States of America. ,vol. 78, pp. 2053- 2056 ,(1981) , 10.1073/PNAS.78.4.2053
James K. GIERSE, Carol M. KOBOLDT, Mark C. WALKER, Karen SEIBERT, Peter C. ISAKSON, Kinetic basis for selective inhibition of cyclo-oxygenases. Biochemical Journal. ,vol. 339, pp. 607- 614 ,(1999) , 10.1042/BJ3390607