Transcription and RNAi in heterochromatic gene silencing
作者： Marc Bühler , Danesh Moazed
DOI: 10.1038/NSMB1315
关键词:
摘要: Recent findings have challenged the longstanding belief that heterochromatin is an inert and transcriptionally inactive structure. Studies in organisms ranging from fission yeast to animals found noncoding RNAs transcribed heterochromatic DNA repeats function assembly of heterochromatin. In this review, we discuss roles RNA turnover mechanisms mediate keep domains silent.
nature.com
core.ac.uk
researchgate.net 
sci-hub.se 参考文章(100)
Roger D Kornberg, Yahli Lorch, Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome Cell. ,vol. 98, pp. 285- 294 ,(1999) , 10.1016/S0092-8674(00)81958-3
C. D. Smith, S. Shu, C. J. Mungall, G. H. Karpen, The Release 5.1 annotation of Drosophila melanogaster heterochromatin. Science. ,vol. 316, pp. 1586- 1591 ,(2007) , 10.1126/SCIENCE.1139815
Carlo Cogoni, Unifying homology effects. Nature Genetics. ,vol. 30, pp. 245- 246 ,(2002) , 10.1038/NG0302-245
Tomoyasu Sugiyama, Hugh P. Cam, Rie Sugiyama, Ken-ichi Noma, Martin Zofall, Ryuji Kobayashi, Shiv I.S. Grewal, SHREC, an Effector Complex for Heterochromatic Transcriptional Silencing Cell. ,vol. 128, pp. 491- 504 ,(2007) , 10.1016/J.CELL.2006.12.035
Vincenzo Pirrotta, David S. Gross, Epigenetic Silencing Mechanisms in Budding Yeast and Fruit Fly: Different Paths, Same Destinations Molecular Cell. ,vol. 18, pp. 395- 398 ,(2005) , 10.1016/J.MOLCEL.2005.04.013
Andrew J Hamilton, David C Baulcombe, A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants Science. ,vol. 286, pp. 950- 952 ,(1999) , 10.1126/SCIENCE.286.5441.950
Daniel H Kim, Louisa M Villeneuve, Kevin V Morris, John J Rossi, Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells Nature Structural & Molecular Biology. ,vol. 13, pp. 793- 797 ,(2006) , 10.1038/NSMB1142
Tony Kouzarides, Chromatin Modifications and Their Function Cell. ,vol. 128, pp. 693- 705 ,(2007) , 10.1016/J.CELL.2007.02.005
Hiroaki Murakami, Derek B. Goto, Takashi Toda, Ee Sin Chen, Shiv I. Grewal, Robert A. Martienssen, Mitsuhiro Yanagida, Ribonuclease Activity of Dis3 Is Required for Mitotic Progression and Provides a Possible Link between Heterochromatin and Kinetochore Function PLoS ONE. ,vol. 2, pp. e317- ,(2007) , 10.1371/JOURNAL.PONE.0000317
C. A. Davis, M. Ares, Accumulation of unstable promoter-associated transcripts upon loss of the nuclear exosome subunit Rrp6p in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 3262- 3267 ,(2006) , 10.1073/PNAS.0507783103