Mitoxantrone, More than Just Another Topoisomerase II Poison.
作者： Benny J. Evison , Brad E. Sleebs , Keith G. Watson , Don R. Phillips , Suzanne M. Cutts
DOI: 10.1002/MED.21364
关键词:
摘要: … topoisomerase IIβ is a molecular target of doxorubicin in cardiomyocytes. Doxorubicin can poison both topoisomerase II … (B) Reactive oxygen species (ROS) may form via enzymatic …
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