Die Bedeutung des Endothels für die Gefäßregulation
作者： E. Bassenge , G. Trogisch
DOI: 10.1007/978-3-642-71486-3_3
关键词:
摘要: Wahrend ursprunglich das Endothel in erster Linie als stoffwechselinaktive Barriere mit antithrombogenen Eigenschaften gesehen wurde, sind heute zwei Prinzipien bekannt, uber die aktiv an der Regulation des Gefastonus beteiligt ist: 1. Aktive Aufnahme und/oder Metabolisierung vasoaktiver Substanzen wie biogene Amine (Serotonin, Noradrenalin), Peptide (Angiotensin, Bradykinin) und Ade-ninnukleotide (uber endotheliale Ektoenzyme); 2. Bildung Freisetzung Autakoide (Prostazyklin andere Pro-staglandine, PAF = „platelet activating factor“ EDRF „endothelium- derived relaxant factor“) [1-3].
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