The Use of Urinary Hormonal Assessments in Human Studies

作者: B. L. LASLEY , K. MOBED , E. B. GOLD

DOI: 10.1111/J.1749-6632.1994.TB30418.X

关键词:

摘要: The collection and analysis of urine samples provides a practical method for monitoring female reproductive events in non-laboratory non-clinic populations. Collection biologic permits objective assessment health endpoints epidemiologic studies research purposes can provide validation information provided by the subjects, especially outcomes which are usually concealed thus unknown to participant. Urine sampling has several advantages over blood samples, such as simplicity, non-invasiveness, cost efficiency. Several have shown that endocrine similar obtained be from assays daily samples. measurement human chorionic gonadotropin selected been incorporated into recent focusing on early fetal loss, ovarian pituitary hormone metabolites measured evaluate function women's health. As strategy urinary becomes more accepted legitimate tool, laboratory methods being modified improve performance, reduce costs adapted sophisticated algorithms using multiple hormonal measurements identify number end-points.

参考文章(29)
Frank Z. Stanczyk, Isao Miyakawa, Uwe Goebelsmann, Direct radioimmunoassay of urinary estrogen and pregnanediol glucuronides during the menstrual cycle American Journal of Obstetrics and Gynecology. ,vol. 137, pp. 443- 450 ,(1980) , 10.1016/0002-9378(80)91125-4
Nancy J. Ellish, Hao-Chia Chen, Casey Jason, Dwight T. Janerich, Pilot study to detect early pregnancy and early fetal loss. Journal of Occupational and Environmental Medicine. ,vol. 28, pp. 1069- 1073 ,(1986) , 10.1097/00043764-198610000-00030
P.F. Daels, D.C. Ammon, G.H. Stabenfeldt, I.K.M. Liu, J.P. Hughes, B.L. Lasley, URINARY AND PLASMA ESTROGEN CONJUGATES, ESTRADIOL AND ESTRONE CONCENTRATIONS IN NONPREGNANT AND EARLY PREGNANT MARES Theriogenology. ,vol. 35, pp. 1001- 1017 ,(1991) , 10.1016/0093-691X(91)90310-A
G. W. DE VANE, N. M. CZEKALA, S. E. SHIDELER, F. C. RIGGALL, B. L. LASLEY, Monitoring gonadotropin-releasing hormone administration by measurement of urinary steroid conjugates. Obstetrics & Gynecology. ,vol. 67, pp. 710- 717 ,(1987) , 10.1097/00006250-198605000-00020
J. F. Kirkpatrick, V. Kincy, K. Bancroft, S. E. Shideler, B. L. Lasley, Oestrous cycle of the North American bison (Bison bison) characterized by urinary pregnanediol-3-glucuronide. Reproduction. ,vol. 93, pp. 541- 547 ,(1991) , 10.1530/JRF.0.0930541
Leonard Chiazze, The Length and Variability of the Human Menstrual Cycle JAMA: The Journal of the American Medical Association. ,vol. 203, pp. 377- 380 ,(1968) , 10.1001/JAMA.1968.03140060001001
Christine M. Branch, Patricia O. Collins, M. J. Kilpatrick, W. P. Collins, The effect of conception on the concentration of urinary oestrone-3-glucuronide, LH/hCG and pregnanediol-3 alpha-glucuronide. European Journal of Endocrinology. ,vol. 93, pp. 228- 233 ,(1980) , 10.1530/ACTA.0.0930228
S.E. Shideler, G.W. DeVane, P.S. Kalra, K. Benirschke, B.L. Lasley, Ovarian-pituitary hormone interactions during the perimenopause Maturitas. ,vol. 11, pp. 331- 339 ,(1989) , 10.1016/0378-5122(89)90029-7