ASYMMETRIC MEMBRANE CAPSULE (AMC): AN USEFUL OSMOTIC DRUG DELIVERY SYSTEM
作者： Ankush Kumar , Deepa Parashar , Sulekha Bhadra , Lalit Kumar
DOI:
关键词:
摘要: Osmotic drug delivery mechanism is well known in the field of oral controlled release systems. The from osmotic devices based on phenomenon osmosis. An useful technology developed for asymmetric membrane capsule (AMC), which an economic and effective device as compared to other existing technique like tablets. It can be prepared by a simple process Phase Inversion. system show less bioavailability fluctuation conventional (CR) systems because it releases independent gastrointestinal (GI) physiological factors. Asymmetric using water insoluble polymer ethyl cellulose (EC), acetate (CA), butyrate (CAB). In this role osmogen important it. Both soluble or drugs delivered AMC. Various categories that formulated AMC are NSAIDS, cardiovascular drugs, anti-diabetic antibiotics etc. This article presents overview dosage form various drugs.
ijppsjournal.com参考文章(25)
A.G Thombre, J.R Cardinal, A.R DeNoto, S.M Herbig, K.L Smith, Asymmetric membrane capsules for osmotic drug delivery: I. Development of a manufacturing process Journal of Controlled Release. ,vol. 57, pp. 55- 64 ,(1999) , 10.1016/S0168-3659(98)00100-X
Devesh Kapoor, Formulation And Evaluation Of Controlled Porosity Osmotic Pump Of Valsartan International Journal of Pharmaceutical & Biological Archive. ,vol. 2, ,(2011)
Sapna N Makhija, Pradeep R Vavia, Controlled porosity osmotic pump-based controlled release systems of pseudoephedrine. I. Cellulose acetate as a semipermeable membrane. Journal of Controlled Release. ,vol. 89, pp. 5- 18 ,(2003) , 10.1016/S0168-3659(02)00482-0
AK Philip, Kamla Pathak, In situ formed phase transited drug delivery system of ketoprofen for achieving osmotic, controlled and level a in vitro in vivo correlation. Indian Journal of Pharmaceutical Sciences. ,vol. 70, pp. 745- 753 ,(2008) , 10.4103/0250-474X.49096
A.G. Thombre, J.R. Cardinal, A.R. DeNoto, D.C. Gibbes, Asymmetric membrane capsules for osmotic drug delivery II. In vitro and in vivo drug release performance. Journal of Controlled Release. ,vol. 57, pp. 65- 73 ,(1999) , 10.1016/S0168-3659(98)00101-1
SM Herbig, JR Cardinal, RW Korsmeyer, KL Smith, None, Asymmetric-membrane tablet coatings for osmotic drug delivery Journal of Controlled Release. ,vol. 35, pp. 127- 136 ,(1995) , 10.1016/0168-3659(95)00028-7
Gaylen M. Zentner, Gerald S. Rork, Kenneth J. Himmelstein, Osmotic flow through controlled porosity films: An approach to delivery of water soluble compounds Journal of Controlled Release. ,vol. 2, pp. 217- 229 ,(1985) , 10.1016/0168-3659(85)90047-1
Michael Weintraub, Gerald Ginsberg, E Carol Stein, P R Sundaresan, Barbara Schuster, Patrick O'Connor, Louise M Byrne, Phenylpropanolamine OROS (Acutrim) vs. placebo in combination with caloric restriction and physician‐managed behavior modification Clinical Pharmacology & Therapeutics. ,vol. 39, pp. 501- 509 ,(1986) , 10.1038/CLPT.1986.87
Y Lin, Investigations on the drug releasing mechanism from an asymmetric membrane-coated capsule with an in situ formed delivery orifice. Journal of Controlled Release. ,vol. 89, pp. 57- 69 ,(2003) , 10.1016/S0168-3659(03)00091-9
D. Prabakaran, Paramjit Singh, K.S. Jaganathan, Suresh P. Vyas, Osmotically regulated asymmetric capsular systems for simultaneous sustained delivery of anti-tubercular drugs. Journal of Controlled Release. ,vol. 95, pp. 239- 248 ,(2004) , 10.1016/J.JCONREL.2003.11.013