Multidrug-resistant bacterial infections after liver transplantation: an ever-growing challenge.

摘要: Bacterial infections are a leading cause of morbidity and mortality among solid organ transplant recipients. Over the last two decades, various multidrug-resistant (MDR) pathogens have emerged as relevant causes infection in this population. Although fact reflects spread MDR health care facilities worldwide, several factors relating to donor candidates recipients render these patients particularly prone acquisition bacteria increase likelihood infectious outbreaks units. The awareness high vulnerability leads more frequent use broad-spectrum empiric antibiotic therapy, which further contributes selection drug resistance. This vicious cycle is difficult avoid scenario increased complexity narrowed therapeutic options. Infection by frequently associated with failure start appropriate antimicrobial therapy. lack treatment may contribute occurring infections. Furthermore, rates been observed infected extensively-resistant pathogens, such carbapenem-resistant Enterobacteriaceae, for optimal remains undefined. In context, careful implementation preventive strategies utmost importance minimize negative impact that on outcome liver article reviews current literature regarding incidence recipients, summarizes recommendations.