Arabidopsis Exocyst Subcomplex Containing Subunit EXO70B1 Is Involved in Autophagy-Related Transport to the Vacuole
作者： Ivan Kulich , Tamara Pečenková , Juraj Sekereš , Ondřej Smetana , Matyáš Fendrych
DOI: 10.1111/TRA.12101
关键词:
摘要: Autophagic transport to the vacuole represents an endomembrane trafficking route, which is widely used in plants, not only during stress situations, but also for biogenesis and developmental processes. Here we report a role autophagic membrane EXO70B1—one of 23 paralogs Arabidopsis EXO70 exocyst subunits. EXO70B1 positive compartments are internalized into central co-localize with autophagosomal marker ATG8f. This internalization boosted by induction autophagy. Loss function (LOF) mutations exo70B1 cause reduction autopagic bodies vacuole. Mutant plants show ectopic hypersensitive response (HR) mediated salicylic acid (SA) accumulation, increased nitrogen starvation susceptibility anthocyanin accumulation defects. Anthocyanin defect persists npr1x double mutants SA signaling compromised, while HR suppressed. interacts SEC5 EXO84 forms subcomplex involved autophagy-related, Golgi-independent traffic We that functionally completely different from EXO70A1 subunit adopted specific transport.
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