Salt intake and hypertensive renal injury in African-Americans: A therapeutic perspective

摘要: Hypertensive renal injury is a major identifiable cause of end-stage disease in African-Americans. A complex nexus sociologic, biologic, environmental, and sociocultural variables are involved mediating this risk interrelate with dietary salt consumption sensitivity. It likely that intake sensitivity linked influencing the hypertensive injury, since it has been demonstrated increasing salt-sensitive patients such as African-Americans results an increase glomerular filtration fraction proteinuria. Dietary influences both carbohydrate metabolism blood pressure, either directly or through its influence on other ions calcium potassium. The interrelationship between pharmacologic interventions important clinical issue, efficacy these therapies influenced by amount diet. also changes pressure induced greater may be more specifically corrected some nonpharmacologic compared to others. Since hemodynamics, metabolism, overall effect cardiovascular risk, particularly high-risk groups African-Americans, assumes importance.