The impact of an N1 lymph node examination in patients with early-stage non-small cell lung cancer: a retrospective cohort study.

摘要: Background The examination of lymph nodes (LNs) is critical for accurate node staging in patients with non-small cell lung cancer (NSCLC), but a consensus on the examinations hilar and intrapulmonary (N1 station) LNs has not been reached. This study aimed to evaluate role LN dissection pathological N1 stations their effects survival stage IA-IIA NSCLC. Methods Data from pathologically staged as who underwent radical surgery confirmed lacking metastases January 2008 March 2018 were retrospectively reviewed. Kaplan-Meier method was used determine overall (OS) disease-free (DFS). After propensity score matching (PSM), Cox model prognostic factors. Results Of 1,935 investigated, median number examined 3. Patients at least 2 had apparently better OS (P=0.002) DFS (P=0.001). All divided into 0-1 station 2-5 examined. PSM, an independent factor (P=0.004). experienced prolonged (P=0.010). group 12 (P=0.021) (P=0.026). 13 or 14 (P=0.028). Conclusions A larger extent associated NSCLC after lobectomy. included lobar segmental drainage fields.