Encoding seasonal information in a two-oscillator model of the multi-oscillator circadian clock.

摘要: The suprachiasmatic nucleus (SCN) is a collection of about 10 000 neurons, each which functions as circadian clock with slightly different periods and phases, that work in concert form maintain the master for organism. diversity among neurons confers on SCN ability to robustly encode both 24-h light pattern well seasonal time. Cluster synchronization brings into line reduces large population essentially two oscillators, coordinated by macroscopic network motif asymmetric repulsive-attractive coupling. We recount steps leading this simplification rigorously examine two-oscillator case seeking an analytical solution. Through these steps, we identify physiologically relevant parameters shape behaviour delineate its store past details variation photoperiod.