Should thyroxine treatment be discontinued for four weeks before 131I thyroid ablation

摘要: Abstract Background It is a usual practice to discontinue thyroxine treatment for four weeks before 131I ablation. Symptoms of hypothyroidism usually occur during this time. Use rhTSH helpful alternative in some cases, but problems availability agent 2012 will limit its use. Patients and methods Plasma TSH FT4 levels were measured on days 7, 14, 21, 28 after total thyroidectomy (12 patients) or discontinuation (20 patients). A Mann–Whitney U-test was used compare quantitative variables, Chi-square test nominal variables. Results On day 30 μIU/mL higher 71% patients (66% the group 75% discontinued treatment). almost all from both groups (91% 100% treatment) had higher. most below normal range. Conclusions Discontinuation not required. Fourteen an adequate time patients, 21 are sufficient virtually patients.