摘要: En oncologie, la recherche de mutations somatiques a visee theranostique est devenue regle pour prescription certaines therapies ciblees. Dans le cas du cancer colorectal, des genes RAS essentielle decision therapeutique, statut sauvage etant necessaire assurer l’efficacite anti-EGFR (cetuximab et panitumumab) [1, 2]. De meme, gefitinib ne peut etre prescrit qu’aux patients presentant une mutation activatrice l’EGFR dans les cancers bronchiques non petites cellules [3]. La mise en evidence nouveaux biomarqueurs joue un role important l’evaluation reponse aux traitements expliquant place plus importante qu’occupe biologie moleculaire oncologie. caracterisation tumeurs permet predire D’ou necessite developper techniques detection sensibles, rapides performantes, l’objectif actuel fournir therapeutique personnalisee possible, adaptee chaque type tumeur patient.
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