Myoblast transfer improves muscle genetics/structure/function and normalizes the behavior and life-span of dystrophic mice.
作者： Peter K. Law , Tena G. Goodwin , H.-J. Li , Ghaith Ajamoughli , Ming Chen
DOI: 10.1007/978-1-4684-5865-7_10
关键词:
摘要: Dystrophic cells degenerate because they lack the normal genome. In our laboratory, transplant techniques have been developed to facilitate cell survival and fusion, such that genome can be incorporated back into dystrophic muscle1–6.
springer.com
sci-hub.st 参考文章(9)
Hans Meier, Janice L. Southard, Muscular dystrophy in the mouse caused by an allele at the dy-locus. Life Sciences. ,vol. 9, pp. 137- 144 ,(1970) , 10.1016/0024-3205(70)90306-1
P.K. Law, H.L. Atwood, A.J. McComas, Functional denervation in the soleus muscle of dystrophic mice Experimental Neurology. ,vol. 51, pp. 434- 443 ,(1976) , 10.1016/0014-4886(76)90267-3
P.K. Law, H.L. Atwood, Nonequivalence of surgical and natural denervation in dystrophic mouse muscles. Experimental Neurology. ,vol. 34, pp. 200- 209 ,(1972) , 10.1016/0014-4886(72)90167-7
Peter K. Law, John L. Yap, New muscle transplant method produces normal twitch tension in dystrophic muscle. Muscle & Nerve. ,vol. 2, pp. 356- 363 ,(1979) , 10.1002/MUS.880020506
Peter K. Law, Ethel Cosmos, Jane Butler, Alan J. McComas, The absence of dystrophic characteristics in normal muscles successfully cross-reinnervated by nerves of dystrophic genotype: Physiological and cytochemical study of crossed solei of normal and dystrophic parabiotic mice Experimental Neurology. ,vol. 51, pp. 1- 21 ,(1976) , 10.1016/0014-4886(76)90050-9
Peter K. Law, Tena G. Goodwin, Mary G. Wang, Normal myoblast injections provide genetic treatment for murine dystrophy. Muscle & Nerve. ,vol. 11, pp. 525- 533 ,(1988) , 10.1002/MUS.880110602
Goodwin Tg, Li Hj, Law Pk, Histoincompatible myoblast injection improves muscle structure and function of dystrophic mice. Transplantation proceedings. ,vol. 20, pp. 1114- ,(1988)
Peter K. Law, Beneficial effects of transplanting normal limb-bud mesenchyme into dystrophic mouse muscles. Muscle & Nerve. ,vol. 5, pp. 619- 627 ,(1982) , 10.1002/MUS.880050806
Peter K. Law, Reduced regenerative capability of minced dystrophic mouse muscles Experimental Neurology. ,vol. 60, pp. 231- 243 ,(1978) , 10.1016/0014-4886(78)90079-1