Nutritional interventions for the prevention of maternal morbidity

摘要: Abstract Objective: To review the effectiveness of nutritional interventions to prevent maternal morbidity. Methods: This is an overview systematic reviews and individual randomized controlled trials (if no available) during pregnancy. For each nutrient intervention main morbidity data reported were extracted. These pre-eclampsia/eclampsia, pregnancy-induced hypertension, hemorrhage, anemia, infection obstructed labor. In addition, trial settings, number participants' characteristics systematically Results: The considered in this paper had only few that selected outcomes. Outcome measures are based sometimes on one only. Most compared single micronutrient supplementation with placebo/no treatment did not show significant benefits for groups. Calcium women at high risk pregnancy hypertension reduced incidence blood pressure (RR, 0.35; 95% CI, 0.21 – 0.57) pre-eclampsia 0.22; 0.11 0.43). Similarly, low dietary calcium intake, resulted a reduction 0.49; 0.38 0.62) 0.32; 0.49). or adequate baseline beneficial effects small unlikely be clinical significance. Both, iron folate pre-delivery hemoglobin. Conclusions: Routine seems promising pregnant developing preeclampsia have but these findings need confirmed power different settings. populations anemia routine should recommended ante-natal care. It unclear stage if adding vitamin A prevalent areas provides further benefits. There inadequate harms adequately nourished populations. With regard other supplementation, such as zinc, magnesium fish oil, sufficient detect clinically important differences infant outcomes needed.