Clinical and molecular investigation of a canine distemper outbreak and vector-borne infections in a group of rescue dogs imported from Hungary to Switzerland

摘要: Canine distemper virus (CDV) is a major pathogen of dogs and wild carnivores worldwide. In Switzerland, in domestic rarely reported. recent years, the import from Eastern Europe to Switzerland has steadily increased. present study, we describe outbreak 15 rescue that were imported Hungary by an animal welfare organisation. The data on vaccination medical history recorded (14 dogs), samples collected investigate CDV vector-borne infections (13 dogs) canine parvovirus infection (12 dogs). monitored for six months. One dog was euthanised directly after import. Thirteen showed clinical signs arrival, i.e., diarrhoea (57 %), coughing (43 %) nasal and/or ocular discharge (21 %); radiographic findings compatible with bronchopneumonia four dogs. diagnosed 11 (85 %); 10 (91 %) tested PCR-positive conjunctival swabs. Vector-borne (Babesia spp., Leishmania infantum, Dirofilaria immitis) found 4 (31 %). Three hospitalized, received ambulatory therapy up two months until recovery. None developed neurological disease. shedding detected period Because put under strict quarantine ceased, did not spread any other isolates 99 % sequence identity HA gene among each belonged Arctic-like lineage CDV. study highlights imminent risks spreading contagious viral through non-selective sick incomplete Europe. several cessation signs, which emphasised roles asymptomatic carriers epidemiology. A long-term follow-up using sensitive PCR measures upmost importance preventing infection. Dog owners organisations should be educated regarding complete vaccinations impact imports pathogens.