Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis.

作者: W. Shi , X. Zhang , X. Jiang , H. Yuan , J. S. Lee

DOI: 10.1126/SCIENCE.1208813

关键词:

摘要: Pyrazinamide (PZA) is a first-line tuberculosis drug that plays a unique role in shortening the duration of tuberculosis chemotherapy. PZA is hydrolyzed intracellularly to pyrazinoic acid (…

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