Cancer drug discovery by repurposing: teaching new tricks to old dogs

作者: Subash C. Gupta , Bokyung Sung , Sahdeo Prasad , Lauren J. Webb , Bharat B. Aggarwal

DOI: 10.1016/J.TIPS.2013.06.005

关键词:

摘要: … is required while taking this NSAID as an anticancer drug … , interest in finding new uses for old drugs has grown among … In this review, we have discussed several defined drugs and …

参考文章(84)
M. T. Drake, S. C. L. M. Cremers, Bisphosphonate therapeutics in bone disease: the hard and soft data on osteoclast inhibition. Molecular Interventions. ,vol. 10, pp. 141- 152 ,(2010) , 10.1124/MI.10.3.5
Takashi Ichiyama, Kuniyuki Okada, James M Lipton, Tomoyo Matsubara, Takashi Hayashi, Susumu Furukawa, Sodium valproate inhibits production of TNF-α and IL-6 and activation of NF-κB Brain Research. ,vol. 857, pp. 246- 251 ,(2000) , 10.1016/S0006-8993(99)02439-7
Hongchao Jiang, Jori E. Taggart, Xiaoxi Zhang, Doris M. Benbrook, Stuart E. Lind, Wei-Qun Ding, Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline) Cancer Letters. ,vol. 312, pp. 11- 17 ,(2011) , 10.1016/J.CANLET.2011.06.032
K. Ye, Y. Ke, N. Keshava, J. Shanks, J. A. Kapp, R. R. Tekmal, J. Petros, H. C. Joshi, Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 1601- 1606 ,(1998) , 10.1073/PNAS.95.4.1601
Richard L. Elliott, Four Lessons from Global Health Drug Discovery: Medicine for an Ailing Industry? ACS Medicinal Chemistry Letters. ,vol. 3, pp. 688- 690 ,(2012) , 10.1021/ML3002105
John Arrowsmith, Trial watch: Phase II failures: 2008–2010 Nature Reviews Drug Discovery. ,vol. 10, pp. 328- 329 ,(2011) , 10.1038/NRD3439
Jayne A. Keifer, Denis C. Guttridge, Brian P. Ashburner, Albert S. Baldwin, Inhibition of NF-κB Activity by Thalidomide through Suppression of IκB Kinase Activity Journal of Biological Chemistry. ,vol. 276, pp. 22382- 22387 ,(2001) , 10.1074/JBC.M100938200
M. S. Boguski, K. D. Mandl, V. P. Sukhatme, Repurposing with a Difference Science. ,vol. 324, pp. 1394- 1395 ,(2009) , 10.1126/SCIENCE.1169920
Patricia F. Coogan, Jacquelyn Smith, Lynn Rosenberg, Statin use and risk of colorectal cancer. Journal of the National Cancer Institute. ,vol. 99, pp. 32- 40 ,(2007) , 10.1093/JNCI/DJK003
Malgorzata Mackiewicz-Wysocka, Magdalena Pankowska, Piotr J Wysocki, Progress in the treatment of bone metastases in cancer patients Expert Opinion on Investigational Drugs. ,vol. 21, pp. 785- 795 ,(2012) , 10.1517/13543784.2012.679928