The Cytolytic P2Z Receptor for Extracellular ATP Identified as a P2X Receptor (P2X7)
作者： A. Surprenant , F. Rassendren , E. Kawashima , R. A. North , G. Buell
DOI: 10.1126/SCIENCE.272.5262.735
关键词:
摘要: … (B) ATPinduced currents in P2X7 expressing HEK 293 cells are enhanced and prolonged … Programmed cell death (PCD) or apoptosis is an important aspect of embryonic development. …
sciencemag.org
harvard.edu参考文章(22)
SE Hickman, J el Khoury, S Greenberg, I Schieren, SC Silverstein, P2Z adenosine triphosphate receptor activity in cultured human monocyte-derived macrophages. Blood. ,vol. 84, pp. 2452- 2456 ,(1994) , 10.1182/BLOOD.V84.8.2452.2452
DK Blanchard, S Wei, C Duan, F Pericle, JI Diaz, JY Djeu, Role of extracellular adenosine triphosphate in the cytotoxic T-lymphocyte-mediated lysis of antigen presenting cells. Blood. ,vol. 85, pp. 3173- 3182 ,(1995) , 10.1182/BLOOD.V85.11.3173.BLOODJOURNAL85113173
T H Steinberg, A S Newman, J A Swanson, S C Silverstein, ATP4- permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes. Journal of Biological Chemistry. ,vol. 262, pp. 8884- 8888 ,(1987) , 10.1016/S0021-9258(18)47497-2
L.C. Nuttle, G.R. Dubyak, Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes. Journal of Biological Chemistry. ,vol. 269, pp. 13988- 13996 ,(1994) , 10.1016/S0021-9258(17)36744-3
M. Murgia, S. Hanau, P. Pizzo, M. Rippa, F. Di Virgilio, Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor. Journal of Biological Chemistry. ,vol. 268, pp. 8199- 8203 ,(1993) , 10.1016/S0021-9258(18)53082-9
G. Buell, C. Lewis, G. Collo, R. A. North, A. Surprenant, An antagonist-insensitive P2X receptor expressed in epithelia and brain. The EMBO Journal. ,vol. 15, pp. 55- 62 ,(1996) , 10.1002/J.1460-2075.1996.TB00333.X
G Collo, RA North, E Kawashima, E Merlo-Pich, S Neidhart, A Surprenant, G Buell, Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels The Journal of Neuroscience. ,vol. 16, pp. 2495- 2507 ,(1996) , 10.1523/JNEUROSCI.16-08-02495.1996
G Buell, R J Evans, A Surprenant, R A North, C Lewis, S Valera, Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors). Molecular Pharmacology. ,vol. 48, pp. 178- 183 ,(1995)
C. Kennedy, P. Leff, How should P2X purinoceptors be classified pharmacologically Trends in Pharmacological Sciences. ,vol. 16, pp. 168- 174 ,(1995) , 10.1016/S0165-6147(00)89010-0
Francesco Di Virgilio, Paola Pizzo, Paola Zanovello, Vincenzo Bronte, Dino Collavo, None, Extracellular ATP as a possible mediator of cell-mediated cytotoxicity Immunology Today. ,vol. 11, pp. 274- 277 ,(1990) , 10.1016/0167-5699(90)90111-L