Extracellular ATP as a possible mediator of cell-mediated cytotoxicity

作者: Francesco Di Virgilio , Paola Pizzo , Paola Zanovello , Vincenzo Bronte , Dino Collavo

DOI: 10.1016/0167-5699(90)90111-L

关键词:

摘要: Abstract Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells lyse target by a specialized mechanism that involves the release of soluble ‘killer' mediators. While several possible mediators have been demonstrated, it is likely others yet to be identified. For more than two decades has known exogenous ATP lytic many cell types. In this article Francesco Di Virgilio colleagues propose extracellular may mediator cytotoxic cell-dependent lysis.

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