Transferrin-oligomers as potential carriers in anticancer drug delivery.
作者： Ching-Jou Lim , Wei-Chiang Shen
DOI: 10.1023/B:PHAM.0000048188.69785.94
关键词:
摘要: Purpose. To investigate if the cross-linking of transferrin receptor (TfR) induced by Tf-oligomers alters endocytosis receptor-ligand complexes in cultured tumor cells and hence increases intracellular drug release.
springer.com
sci-hub.se 参考文章(42)
Garnett Mc, Fitzpatrick Jj, Design, synthesis and in vitro testing of methotrexate carrier conjugates linked via oligopeptide spacers. Anti-cancer Drug Design. ,vol. 10, pp. 1- 9 ,(1995)
Michael Weaver, Douglas W. Laske, Transferrin receptor ligand-targeted toxin conjugate (Tf-CRM107) for therapy of malignant gliomas. Journal of Neuro-oncology. ,vol. 65, pp. 3- 13 ,(2003) , 10.1023/A:1026246500788
V Raso, M Basala, A highly cytotoxic human transferrin-ricin A chain conjugate used to select receptor-modified cells. Journal of Biological Chemistry. ,vol. 259, pp. 1143- 1149 ,(1984) , 10.1016/S0021-9258(17)43579-4
N. Gironès, E. Alverez, A. Seth, I.M. Lin, D.A. Latour, R.J. Davis, Mutational analysis of the cytoplasmic tail of the human transferrin receptor. Identification of a sub-domain that is required for rapid endocytosis. Journal of Biological Chemistry. ,vol. 266, pp. 19006- 19012 ,(1991) , 10.1016/S0021-9258(18)55163-2
G. C. Todd, M. N. Novilla, L. C. Howard, Comparative toxicology of monensin sodium in laboratory animals. Journal of Animal Science. ,vol. 58, pp. 1512- 1517 ,(1984) , 10.2527/JAS1984.5861512X
Barry I. Schweitzer, Adam P. Dicker, Joseph R. Bertino, Dihydrofolate reductase as a therapeutic target The FASEB Journal. ,vol. 4, pp. 2441- 2452 ,(1990) , 10.1096/FASEBJ.4.8.2185970
Vic Raso, Catherine Fehrmann, Vishnu C. Solan, Andre Rosowsky, Monensin is obligatory for the cytotoxic action of a disulfide linked methotrexate-anti-transferrin receptor conjugate Biochemical and Biophysical Research Communications. ,vol. 150, pp. 104- 110 ,(1988) , 10.1016/0006-291X(88)90492-5
Hans J. Geuze, Jan W. Slot, Ger J.A.M. Strous, Jane Peppard, Kurt von Figura, Andrej Hasilik, Alan L. Schwartz, Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver Cell. ,vol. 37, pp. 195- 204 ,(1984) , 10.1016/0092-8674(84)90315-5
C Harding, J Heuser, P Stahl, Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes Journal of Cell Biology. ,vol. 97, pp. 329- 339 ,(1983) , 10.1083/JCB.97.2.329
Ian S. Trowbridge, James F. Collawn, Structural requirements for high efficiency endocytosis of the human transferrin receptor. Journal of Inorganic Biochemistry. ,vol. 47, pp. 209- 217 ,(1992) , 10.1016/0162-0134(92)84066-V