Photoinactivation of Candida albicans and Escherichia coli using aluminium phthalocyanine on gold nanoparticles

作者: Thandekile Mthethwa , Tebello Nyokong

DOI: 10.1039/C4PP00315B

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摘要: The conjugates of aluminium phthalocyanine (complex 1) with gold nanorods 1–AuNRs) and bipyramids 1–AuBPs) showed improved singlet oxygen quantum yields 0.23 0.24, respectively, compared to that complex 1 alone at 0.12. Complex its were used for the photoinactivation fungi (C. albicans) bacteria cells (E. coli). Q band absorbances same Pc when conjugated AuNPs. efficiency these was evaluated by measuring log reduction microorganisms albicans E. coli) after irradiation visible light in presence photosensitizers. Aluminium log1.78 log2.51 reductions C. coli respectively. However, higher photosensitization log2.08 log3.34 coli, respectively using 1–AuBPs. For 1–AuNRs log2.53 log3.71 achieved statistical analysis results enhanced observed both irrespective shape nanoparticles conjugated. Photoinactivation less than even though a concentration or albicans.

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