Influence of iotrolan on renal cortical and outer medullary blood flow in the rat.
作者： Per Liss , Anders Nygren , Peter Hansell
DOI: 10.1016/S1076-6332(98)80080-9
关键词:
摘要: Circulatory events in the renal medulla have been suggested as a possible mechanism underlying contrast medium-induced acute failure (CM-ARF) (1,2). After introduction of so-called low-osmolar CM, there was hope that these compounds would be less nephrotoxic than more hyperosmolar ionic CM. Since is at constant risk hypoxic injury (2-4), we wanted to investigate effects iotrolan, new isoosmolar on regional blood flow cortex and outer medulla. In previous studies, found this dimer decreases oxygen tension (5).
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