Regulation of Ste20-like kinase, SLK, activity: Dimerization and activation segment phosphorylation.

作者: Andrey V. Cybulsky , Julie Guillemette , Joan Papillon , Nihad T. Abouelazm

DOI: 10.1371/JOURNAL.PONE.0177226

关键词:

摘要: … Erlotinib was originally developed as an inhibitor of the epidermal growth factor (EGF) … activity of SLK (and the related lymphocyte-oriented kinase), and to be an effective SLK inhibitor […

参考文章(55)
Eitaro Yamada, Kazutake Tsujikawa, Susumu Itoh, Yo-ichiro Kameda, Yasuhiro Kohama, Hiroshi Yamamoto, Molecular cloning and characterization of a novel human STE20-like kinase, hSLK. Biochimica et Biophysica Acta. ,vol. 1495, pp. 250- 262 ,(2000) , 10.1016/S0167-4889(99)00164-0
Aala Jaberi, Erika Hooker, Julie Guillemette, Joan Papillon, Arnold S. Kristof, Andrey V. Cybulsky, Identification of Tpr and α-actinin-4 as two novel SLK-interacting proteins Biochimica et Biophysica Acta. ,vol. 1853, pp. 2539- 2552 ,(2015) , 10.1016/J.BBAMCR.2015.06.005
David J. Salant, Andrey V. Cybulsky, [38] Experimental glomerulonephritis Methods in Enzymology. ,vol. 162, pp. 421- 461 ,(1988) , 10.1016/0076-6879(88)62096-9
Laura Conradt, Klaus Godl, Christoph Schaab, Andreas Tebbe, Stefan Eser, Sandra Diersch, Christoph W. Michalski, Jörg Kleeff, Angelika Schnieke, Roland M. Schmid, Dieter Saur, Günter Schneider, Disclosure of erlotinib as a multikinase inhibitor in pancreatic ductal adenocarcinoma. Neoplasia. ,vol. 13, pp. 1026- 1034 ,(2011) , 10.1593/NEO.111016
Khalid N. Al-Zahrani, Prabhjot Sekhon, Daniel R. Tessier, Julien Yockell-Lelievre, Benjamin R. Pryce, Kyla D. Baron, Grant A. Howe, Roshan K. Sriram, Kate Daniel, Marlene Mckay, Vivian Lo, Jennifer Quizi, Christina L. Addison, Andrée Gruslin, Luc A. Sabourin, Essential role for the SLK protein kinase in embryogenesis and placental tissue development. Developmental Dynamics. ,vol. 243, pp. 640- 651 ,(2014) , 10.1002/DVDY.24106
Gavin I. Welsh, Moin A. Saleem, The podocyte cytoskeleton—key to a functioning glomerulus in health and disease Nature Reviews Nephrology. ,vol. 8, pp. 14- 21 ,(2012) , 10.1038/NRNEPH.2011.151
Andrey V. Cybulsky, Tomoko Takano, Joan Papillon, Julie Guillemette, Andrew M. Herzenberg, Chris R.J. Kennedy, Podocyte Injury and Albuminuria in Mice with Podocyte-Specific Overexpression of the Ste20-Like Kinase, SLK American Journal of Pathology. ,vol. 177, pp. 2290- 2299 ,(2010) , 10.2353/AJPATH.2010.100263
Christophe Guilluy, Malvyne Rolli-Derkinderen, Laurent Loufrani, Anne Bourgé, Daniel Henrion, Luc Sabourin, Gervaise Loirand, Pierre Pacaud, Ste20-Related Kinase SLK Phosphorylates Ser188 of RhoA to Induce Vasodilation in Response to Angiotensin II Type 2 Receptor Activation Circulation Research. ,vol. 102, pp. 1265- 1274 ,(2008) , 10.1161/CIRCRESAHA.107.164764
Simona Wagner, Trevor A. Flood, Paul O'Reilly, Karri Hume, Luc A. Sabourin, Association of the Ste20-like kinase (SLK) with the microtubule. Role in Rac1-mediated regulation of actin dynamics during cell adhesion and spreading. Journal of Biological Chemistry. ,vol. 277, pp. 37685- 37692 ,(2002) , 10.1074/JBC.M205899200
Heidrun Ellinger-Ziegelbauer, Hajime Karasuyama, Eitaro Yamada, Kazutake Tsujikawa, Kazuo Todokoro, Eisuke Nishida, Ste20-like kinase (SLK), a regulatory kinase for polo-like kinase (Plk) during the G2/M transition in somatic cells. Genes to Cells. ,vol. 5, pp. 491- 498 ,(2000) , 10.1046/J.1365-2443.2000.00337.X