Higher incidence of postoperative up-staging in lung micropapillary adenocarcinoma
作者： Hiroyasu Nakashima , Shi-Xu Jiang , Keika Hoshi , Makoto Saegusa , Yukitoshi Satoh
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摘要: Objective: We investigated the association of diagnostic accuracy for preoperative clinical stage lung adenocarcinoma with its histologic subtype micropapillary pattern (MPA) or non-micropapillary (NMPA). Methods: evaluated 303 patients pathologic who underwent 18Ffluorodeoxyglucose positron emission tomography (FDG-PET) scanning, from 2008 to 2013, before undergoing surgical resection. Patients had been and were classified by MPA NMPA. Results: There was a significant difference in postoperative up-staging between NMPA (P < 0.0001) cases. In addition, there frequency upgrading lymph node (N) factor 0.0001), but not tumor (T) = 0.8271). Postoperative N up-grading observed more frequently Conclusion: adenocarcinoma, some metastases undetectable imaging studies and, consequently, patients. While FDG-PET is useful evaluation spread lesion, it necessary conduct treatment while remembering that metastasis difficult detect patients, depending on histological subtype.
参考文章(34)
Akihiko Yoshizawa, Noriko Motoi, Gregory J Riely, Cami S Sima, William L Gerald, Mark G Kris, Bernard J Park, Valerie W Rusch, William D Travis, Impact of proposed IASLC/ATS/ERS classification of lung adenocarcinoma: prognostic subgroups and implications for further revision of staging based on analysis of 514 stage I cases Modern Pathology. ,vol. 24, pp. 653- 664 ,(2011) , 10.1038/MODPATHOL.2010.232
Yihua Wu, Peiwei Li, Honghe Zhang, Yu Shi, Han Wu, Jinjie Zhang, Yufeng Qian, Chao Li, Jun Yang, Diagnostic value of fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography for the detection of metastases in non-small-cell lung cancer patients International Journal of Cancer. ,vol. 132, pp. E37- E47 ,(2013) , 10.1002/IJC.27779
Mahul B. Amin, Jae Y. Ro, T. El-Sharkawy, Kwang M. Lee, Patricia Troncoso, Elvio G. Silva, Nelson G. Ordóñez, Alberto G. Ayala, Micropapillary variant of transitional cell carcinoma of the urinary bladder. Histologic pattern resembling ovarian papillary serous carcinoma. The American Journal of Surgical Pathology. ,vol. 18, pp. 1224- 1232 ,(1994) , 10.1097/00000478-199412000-00005
Takehito Kawakami, Kazuki Nabeshima, Yoshifumi Makimoto, Makoto Hamasaki, Akinori Iwasaki, Takayuki Shirakusa, Hiroshi Iwasaki, Micropapillary pattern and grade of stromal invasion in pT1 adenocarcinoma of the lung: usefulness as prognostic factors. Modern Pathology. ,vol. 20, pp. 514- 521 ,(2007) , 10.1038/MODPATHOL.3800765
Susan S. Devesa, Freddie Bray, A. Paloma Vizcaino, D. Max Parkin, International lung cancer trends by histologic type: Male:Female differences diminishing and adenocarcinoma rates rising International Journal of Cancer. ,vol. 117, pp. 294- 299 ,(2005) , 10.1002/IJC.21183
William D Travis, Elisabeth Brambilla, Masayuki Noguchi, Andrew G Nicholson, Kim R Geisinger, Yasushi Yatabe, David G Beer, Charles A Powell, Gregory J Riely, Paul E Van Schil, Kavita Garg, John HM Austin, Hisao Asamura, Valerie W Rusch, Fred R Hirsch, Giorgio Scagliotti, Tetsuya Mitsudomi, Rudolf M Huber, Yuichi Ishikawa, James Jett, Montserrat Sanchez-Cespedes, Jean-Paul Sculier, Takashi Takahashi, Masahiro Tsuboi, Johan Vansteenkiste, Ignacio Wistuba, Pan-Chyr Yang, Denise Aberle, Christian Brambilla, Douglas Flieder, Wilbur Franklin, Adi Gazdar, Michael Gould, Philip Hasleton, Douglas Henderson, Bruce Johnson, David Johnson, Keith Kerr, Keiko Kuriyama, Jin Soo Lee, Vincent A Miller, Iver Petersen, Victor Roggli, Rafael Rosell, Nagahiro Saijo, Erik Thunnissen, Ming Tsao, David Yankelewitz, None, International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma Journal of Thoracic Oncology. ,vol. 6, pp. 244- 285 ,(2011) , 10.1097/JTO.0B013E318206A221
Michael K. Gould, Ware G. Kuschner, Chara E. Rydzak, Courtney C. Maclean, Anita N. Demas, Hidenobu Shigemitsu, Jo Kay Chan, Douglas K. Owens, Test performance of positron emission tomography and computed tomography for mediastinal staging in patients with non-small-cell lung cancer: a meta-analysis. Annals of Internal Medicine. ,vol. 139, pp. 879- 892 ,(2003) , 10.7326/0003-4819-139-11-200311180-00013
Katsuhiko Shimizu, Yuji Hirami, Shinsuke Saisho, Takuro Yukawa, Ai Maeda, Koichiro Yasuda, Masao Nakata, Maximal standardized uptake value on FDG-PET is correlated with cyclooxygenase-2 expression in patients with lung adenocarcinoma. The Annals of Thoracic Surgery. ,vol. 93, pp. 398- 403 ,(2012) , 10.1016/J.ATHORACSUR.2011.10.033
Angela van Baardwijk, Christophe Dooms, Robert Jan van Suylen, Erik Verbeken, Monique Hochstenbag, Cary Dehing-Oberije, Dennis Rupa, Silvia Pastorekova, Sigrid Stroobants, Ulrich Buell, Philippe Lambin, Johan Vansteenkiste, Dirk De Ruysscher, The maximum uptake of 18F-deoxyglucose on positron emission tomography scan correlates with survival, hypoxia inducible factor-1α and GLUT-1 in non-small cell lung cancer European Journal of Cancer. ,vol. 43, pp. 1392- 1398 ,(2007) , 10.1016/J.EJCA.2007.03.027
Ben A. Dwamena, Seema S. Sonnad, Jeff O. Angobaldo, Richard L. Wahl, Metastases from non-small cell lung cancer: mediastinal staging in the 1990s--meta-analytic comparison of PET and CT. Radiology. ,vol. 213, pp. 530- 536 ,(1999) , 10.1148/RADIOLOGY.213.2.R99NV46530