Evaluation of a warfarin initiation protocol for older people.
作者： T. J. Wilkinson , R. Sainsbury
DOI: 10.1046/J.1445-5994.2003.00452.X
关键词:
摘要: A protocol for initiation of warfarin therapy, targeted specifically older people and based on individual responses to initial doses, was evaluated in a case-control study. People within the group: (i) received higher doses warfarin, (ii) reached an international normalized ratio (INR) 2 more quickly, (iii) spent time with INR 2-3 first week (iv) were less likely be over-anticoagulated. However, proportion who too quickly (in <4 days) no greater. The correctly predicted maintenance dose range over 70% cases.
sci-hub.se 参考文章(15)
A. Oates, P. R. Jackson, C. A. Austin, K. S. Channer, A new regimen for starting warfarin therapy in out-patients British Journal of Clinical Pharmacology. ,vol. 46, pp. 157- 161 ,(1998) , 10.1046/J.1365-2125.1998.00755.X
James L. Sebastian, Donald D. Tresch, Use of Oral Anticoagulants in Older Patients Drugs & Aging. ,vol. 16, pp. 409- 435 ,(2000) , 10.2165/00002512-200016060-00003
A Fennerty, J Dolben, P Thomas, G Backhouse, D P Bentley, I A Campbell, P A Routledge, Flexible induction dose regimen for warfarin and prediction of maintenance dose. BMJ. ,vol. 288, pp. 1268- 1270 ,(1984) , 10.1136/BMJ.288.6426.1268
G.D. Motykie, D. Mokhtee, L.P. Zebala, J.A. Caprini, J.C. Kudrna, D.R. Mungall, The use of a Bayesian forecasting model in the management of warfarin therapy after total hip arthroplasty. Journal of Arthroplasty. ,vol. 14, pp. 988- 993 ,(1999) , 10.1016/S0883-5403(99)90015-3
Mary Beth O'Connell, Paul R. Kowal, Caren J. Allivato, Tanya L. Repka, Evaluation of warfarin initiation regimens in elderly inpatients. Pharmacotherapy. ,vol. 20, pp. 923- 930 ,(2000) , 10.1592/PHCO.20.11.923.35260
J. R. Gladman, G. Dolan, Effect of age upon the induction and maintenance of anticoagulation with warfarin. Postgraduate Medical Journal. ,vol. 71, pp. 153- 155 ,(1995) , 10.1136/PGMJ.71.833.153
M. REDWOOD, CLARE TAYLOR, BARBARA J. BAIN, J. H. MATTHEWS, The Association of Age with Dosage Requirement for Warfarin Age and Ageing. ,vol. 20, pp. 217- 220 ,(1991) , 10.1093/AGEING/20.3.217
L. S. P. WICKRAMASINGHE, S.K. BASU, S.K. BANSAL, LONG-TERM ORAL ANTICOAGULANT THERAPY IN ELDERLY PATIENTS Age and Ageing. ,vol. 17, pp. 388- 396 ,(1988) , 10.1093/AGEING/17.6.388
P. Weiss, G.A. Soff, H. Halkin, U. Seligsohn, Decline of proteins C and S and factors II, VII, IX and X during the initiation of warfarin therapy. Thrombosis Research. ,vol. 45, pp. 783- 790 ,(1987) , 10.1016/0049-3848(87)90088-0
Mark. A. Crowther, Jeff B. Ginsberg, Clive Kearon, Linda Harrison, J. Johnson, M. Patricia Massicotte, Jack Hirsh, A Randomized Trial Comparing 5-mg and 10-mg Warfarin Loading Doses Archives of Internal Medicine. ,vol. 159, pp. 46- 48 ,(1999) , 10.1001/ARCHINTE.159.1.46