Contribution of age, body weight, and CYP2C9 and VKORC1 genotype to the anticoagulant response to warfarin: proposal for a new dosing regimen in Chinese patients

作者: Liyan Miao , Jian Yang , Chenrong Huang , Zhenya Shen

DOI: 10.1007/S00228-007-0381-6

关键词: SurgeryAnticoagulantVitamin K epoxide reductasePharmacogeneticsCYP2C9Vitamin-K-epoxide reductase (warfarin-sensitive)VKORC1Internal medicineBiologyAnthropometryWarfarinPharmacology (medical)PharmacologyGeneral Medicine

摘要: Objective The objective of this study was to assess the contribution VKORC1 and CYP2C9 genotypes age, body size, weight patients warfarin dose requirement in a Chinese population.

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