作者: Leslie Y. Chen , Niclas Eriksson , Rhian Gwilliam , David Bentley , Panos Deloukas
DOI: 10.1182/BLOOD-2005-04-1711
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摘要: Warfarin is the most widely prescribed anticoagulant for thromboembolic therapy, despite a 20-fold interindividual difference in dose requirement and narrow therapeutic range. Incorrect dosage, especially during initial phase of treatment, carries high risk either severe bleeding or