Poly-l-lysine-coated magnetic nanoparticles as intracellular actuators for neural guidance.
作者： Cristina Riggio , Maria Pilar Calatayud , Clare Hoskins , Josephine Pinkernelle , Beatriz Sanz
DOI: 10.2147/IJN.S28460
关键词:
摘要: Purpose It has been proposed in the literature that Fe3O4 magnetic nanoparticles (MNPs) could be exploited to enhance or accelerate nerve regeneration and provide guidance for regenerating axons. MNPs create mechanical tension stimulates growth elongation of Particles suitable this purpose should possess (1) high saturation magnetization, (2) a negligible cytotoxic profile, (3) capacity magnetize mammalian cells. Unfortunately, materials currently available on market do not satisfy these criteria; therefore, work attempts overcome deficiencies.
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sci-hub.se 参考文章(28)
Eun-Jung Park, Hero Kim, Younghun Kim, Jongheop Yi, Kyunghee Choi, Kwangsik Park, Inflammatory responses may be induced by a single intratracheal instillation of iron nanoparticles in mice. Toxicology. ,vol. 275, pp. 65- 71 ,(2010) , 10.1016/J.TOX.2010.06.002
Omid Veiseh, Jonathan W. Gunn, Miqin Zhang, Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging Advanced Drug Delivery Reviews. ,vol. 62, pp. 284- 304 ,(2010) , 10.1016/J.ADDR.2009.11.002
Claire Wilhelm, Florence Gazeau, Universal cell labelling with anionic magnetic nanoparticles. Biomaterials. ,vol. 29, pp. 3161- 3174 ,(2008) , 10.1016/J.BIOMATERIALS.2008.04.016
M Andrés Vergés, R Costo, A G Roca, J F Marco, G F Goya, C J Serna, M P Morales, Uniform and water stable magnetite nanoparticles with diameters around the monodomain-multidomain limit Journal of Physics D. ,vol. 41, pp. 134003- ,(2008) , 10.1088/0022-3727/41/13/134003
R. D. K. Misra, Magnetic nanoparticle carrier for targeted drug delivery: perspective, outlook and design Materials Science and Technology. ,vol. 24, pp. 1011- 1019 ,(2008) , 10.1179/174328408X341690
Giacomo Diaz, Shusen Liu, Raffaella Isola, Angela Maria Falchi, Andrea Diana, Mitochondrial localization of reactive oxygen species by dihydrofluorescein probes. Histochemistry and Cell Biology. ,vol. 120, pp. 319- 325 ,(2003) , 10.1007/S00418-003-0566-8
Jan Riemer, Hans Hermann Hoepken, Hania Czerwinska, Stephen R Robinson, Ralf Dringen, Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells Analytical Biochemistry. ,vol. 331, pp. 370- 375 ,(2004) , 10.1016/J.AB.2004.03.049
J Emerit, C Beaumont, F Trivin, Iron metabolism, free radicals, and oxidative injury Biomedicine & Pharmacotherapy. ,vol. 55, pp. 333- 339 ,(2001) , 10.1016/S0753-3322(01)00068-3
M Kettering, J Winter, M Zeisberger, S Bremer-Streck, H Oehring, C Bergemann, C Alexiou, R Hergt, K J Halbhuber, W A Kaiser, I Hilger, Magnetic nanoparticles as bimodal tools in magnetically induced labelling and magnetic heating of tumour cells: anin vitrostudy Nanotechnology. ,vol. 18, pp. 175101- ,(2007) , 10.1088/0957-4484/18/17/175101
Stefaan J. H. Soenen, Nele Nuytten, Simon F. De Meyer, Stefaan C. De Smedt, Marcel De Cuyper, High Intracellular Iron Oxide Nanoparticle Concentrations Affect Cellular Cytoskeleton and Focal Adhesion Kinase‐Mediated Signaling Small. ,vol. 6, pp. 832- 842 ,(2010) , 10.1002/SMLL.200902084